CRRT | Critical Thinking In Medicine

BICARICU-2: Sodium Bicarbonate reduces need for renal replacement but does not change mortality.

This trial is a follow up to the BICARICU trial which used of sodium bicarbonate in critically ill patients with metabolic acidemia. Primary outcome of mortality was not different; however, renal replacement need was again lower in the intervention group with a NNT of 7.

Martin Cearras, MD

12 hours ago2 min read

BICAR-ICU trial: in a subgroup with severe acidemia and severe Acute Kidney Injury a bicarbonate infusion reduces need for renal replacement therapy and potentially mortality at 28 days.

Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre,...

David Goldenberg, DO

Jan 24 min read

STARRT - AKI trial. Harm and unnecessary Renal Replacement Therapy (RRT) when RRT is started early in the ICU.

Critical Appraisal of the Starrt - AKI trial for early renal replacement in the ICU

Peter Tofts, MD

Oct 22, 20243 min read

BICARICU-2: Sodium Bicarbonate reduces need for renal replacement but does not change mortality.

BICAR-ICU trial: in a subgroup with severe acidemia and severe Acute Kidney Injury a bicarbonate infusion reduces need for renal replacement therapy and potentially mortality at 28 days.

STARRT - AKI trial. Harm and unnecessary Renal Replacement Therapy (RRT) when RRT is started early in the ICU.

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BICARICU-2: Sodium Bicarbonate reduces need for renal replacement but does not change mortality.

BICAR-ICU trial: in a subgroup with severe acidemia and severe Acute Kidney Injury a bicarbonate infusion reduces need for renal replacement therapy and potentially mortality at 28 days.

STARRT - AKI trial. Harm and unnecessary Renal Replacement Therapy (RRT) when RRT is started early in the ICU.

Critical Thinking in Medicine

Join us and be a part of the Critical Thinking in Medicine Team

Help support the website. Every amount counts!

Help support the website.
Every amount counts!