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Evidence Based Medicine Concepts

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Forest Plots and result consistency

How to look at a body of evidence instead of just one result.

Basic EBM, Confidence Intervals, Systematic Review, Outcomes

Likelihood Ratios

The Diagnostician's Best Friend

Basic EBM, Interactive, Diagnosis, Cohort

Likelihood ratio concept page

Subgroup Analysis

Sorry, this drug doesn't work on Geminis.

Subgroup Analysis, Advanced EBM Concept, Bias, Outcomes, RCT, Cohort, Systematic Review

Intention to treat analysis

That is not my mortality - He didn't even go to the OR!

Basic EBM, RCT

Blinding

When, who and what?

Basic EBM, RCT

Funnel Plots and publication bias.

Are they hiding the negative papers in a drawer somewhere?

Advanced EBM Concept, Systematic Review, Bias

Funnel plot description

What is Power?

Why does it matter clinically?

Advanced EBM Concept, Type II error, Study Design, Interactive

Stopping trials early

How a perceived benefit can be harmful down the road

Advanced EBM Concept, Type II error, Type I error

Loss to follow up

How much is too much?

Basic EBM, RCT, Cohort

Composite outcomes.

Useful tool or potentially misleading?

Basic EBM, Outcomes

TIME trial, Syntax trial. Composite outcomes.

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