How to look at a body of evidence instead of just one result.
Forest Plots and result consistency
Basic EBM, Systematic Reviews, Uncertainty, Confidence Intervals
The Diagnostician's Best Friend
Likelihood Ratios
Basic EBM, Interactive, Diagnosis
Sorry, this drug doesn't work on Geminis.
Subgroup Analysis
subgroup analysis, Advanced EBM Concept, Primary outcome, Bias
That is not my mortality - He didn't even go to the OR!
Intention to treat analysis
Basic EBM, RCT
When, who and what?
Blinding
Are they hiding the negative papers in a drawer somewhere?
Funnel Plots and publication bias.
Advanced EBM Concept, Systematic Reviews, Bias
Why does it matter clinically?
What is Power?
Advanced EBM Concept, Type II error, Study Design, Interactive
How a perceived benefit can be harmful down the road
Stopping trials early
Advanced EBM Concept, Type II error, Type I error
How much is too much?
Loss to follow up
Basic EBM, Loss to follow up, RCT, Uncertainty, Bias
Useful tool or potentially misleading?
Composite outcomes.
Basic EBM, Composite Outcomes